Perfluorinated compounds: Emerging POPs with potential immunotoxicity

Perfluorinated Chemicals: an emerging concern

Structural equation modeling of immunotoxicity associated with exposure to perfluorinated alkylates

BACKGROUND Exposure to perfluorinated alkylate substances (PFASs) is associated with immune suppression in animal models, and serum concentrations of specific antibodies against certain childhood vaccines tend to decrease at higher exposures. As such, we investigated the immunotoxic impacts of the three major PFASs in a Faroese birth cohort. METHODS A total of 464 children contributed blood s...

Immunotoxicity of perfluorinated alkylates: calculation of benchmark doses based on serum concentrations in children

BACKGROUND Immune suppression may be a critical effect associated with exposure to perfluorinated compounds (PFCs), as indicated by recent data on vaccine antibody responses in children. Therefore, this information may be crucial when deciding on exposure limits. METHODS Results obtained from follow-up of a Faroese birth cohort were used. Serum-PFC concentrations were measured at age 5 years,...

Potential exposure of perfluorinated compounds to Chinese in Shenyang and Yangtze River Delta areas

A total of 21 perfluorinated compounds (PFCs) were quantified in water and biota samples collected from Shenyang in North-east China and the Yangtze River Delta area in East China. The human health risk owing to intake of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) via fish and domestic poultry dietarywas evaluated. The total PFC concentration ( P PFC) in water samples fr...

Sensitive colorimetric visualization of perfluorinated compounds using poly(ethylene glycol) and perfluorinated thiols modified gold nanoparticles.

In this work, we have developed a novel sensing strategy employing mixed poly(ethylene glycol)-terminated (PEG-thiols) and perfluoroalkyl-terminated (F-thiols) alkanethiols modified gold nanoparticles (Au@PEG-F NPs) as a probe to detect perfluorinated compounds (PFCs) from water samples. PEG-thiols with high density and long carbon chains make the Au NPs probe well-dispersed in solution and sta...